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Title: | Accumulation of Tritium and Other Undesirable β-Emitting Radionuclides in the Production of Radiopharmaceuticals for PET Diagnostics |
Authors: | Brinkevich, S. D. Brinkevich, D. I. Kiyavitskaya, H. I. Kiyko, A.N. |
Keywords: | ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Физика ЭБ БГУ::ТЕХНИЧЕСКИЕ И ПРИКЛАДНЫЕ НАУКИ. ОТРАСЛИ ЭКОНОМИКИ::Медицина и здравоохранение ЭБ БГУ::ТЕХНИЧЕСКИЕ И ПРИКЛАДНЫЕ НАУКИ. ОТРАСЛИ ЭКОНОМИКИ::Ядерная техника ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Химия |
Issue Date: | 1-Jan-2023 |
Publisher: | Pleiades Publishing, Ltd. |
Citation: | Physics of Atomic Nuclei. – 2023. – Vol. 86, No. 10. – P. 1–6. |
Abstract: | The article deals with the problem of formation of undesirable β-emitting radionuclides (RNs) in the production of radiopharmaceuticals for PET diagnostics. It is found that tritium is the main trace RN formed by the reaction 18^O(p,t)16^O during irradiation of water [18^O]H2O with protons. Other trace β emitters in water accumulate mainly as a result of leaching of activated target wall materials. The possibility of using the activity of tritium in water [18^O]H2O as an indicator of its re-enrichment is shown. The necessity of controlling the content of trace β-emitting RNs in intermediate products, production waste, and final radiopharmaceuticals is demonstrated. |
URI: | https://elib.bsu.by/handle/123456789/305286 |
ISSN: | 1063-7788 (Print) 1562-692X (Electronic) |
DOI: | 10.1134/S1063778823100101 |
Licence: | info:eu-repo/semantics/restrictedAccess |
Appears in Collections: | Кафедра физики полупроводников и наноэлектроники (статьи) |
Files in This Item:
File | Description | Size | Format | |
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NuclPhys2310010BrinkevichKOR.pdf | 247,67 kB | Adobe PDF | View/Open |
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