Simulation and Analytical Models for the Analysis of In Vitro Actin Polymerization

Abstract

The processes of actin polymerization have significant importance for different biological processes, such as cell cytoskeleton formation and cell motility. However, analytical analysis of the experimental data from these systems gives only rough estimations and has many limitations. In this paper the simulation formalism for the subsequent experimental data processing is proposed and the simulation model developed. The validation of the model has been performed by the comparison of the simulated results with the analytical prediction for the simplest situation.