Изучение фенотипической антибиотикорезистентности, а также генов патогенности штаммов s. Pyogenes, циркулирующих на территории г. Минска

Abstract

The aim of our research was a study of genes of pathogenicity prtF1 and sic, and also phenotypical antibiotic resistance of the clinical strains of S.pyogenes, isolated from patients which have streptococcal assotiated diseases in the territory of Minsk.With the help of these methods has been studied 50 strains of S.pyogenes isolated from patients with different localization of streptococcal assotiated diseases. As a result of the conducted research, it was found that, 23 (46%) strains of S.pyogenes did not contain the studied gene pathogenicity (prtF1 and sic), 11 (22%) of the studied isolates was detected only sic gene, in 9 (18%) - only prtF1 gene, and 7 (14%) of the 50 strains studied had both studied gene pathogenicity (sic and prtF1).We have also studied the phenotypic antibiotic resistance 50 strains of S.pyogenes to ampicillin, clindamycin, erythromycin, tetracycline, chloramphenicol, and cephalothin.