Роль эпидемического штамма вируса h1n1 в заболеваемости гриппом в постпандемический период

Abstract

We have determined that after pandemics flu morbidity is mostly caused by epidemic influenza A H1N1 and season H3N2 influenza; epidemic influenza A H1N1 hasn’t changed after the pandemics; season influenza A H1N1 strains don’t circulate after the pandemics, so vaccines which were applied till 2010 didn’t prevent flu diseases; human influenza A H1N1 often reassorts with animal influenza A (mostly with swine) and sometimes with other human strains. We found out that human epidemic influenza A H1N1 could easily cause desease among animals, despite interspecies barrier. Segment is the basic unit of the reassortation. Mutation rates of different genes inside one segment are different.