Теоретические и экспериментальные исследования волноводных систем с кольцевым рабочим элементом для воздействия акустической энергией на биологические ткани

Abstract

The article presents novel method of combined therapy of superficial tumours based on excitation of ultrasonic waves in tumour tissues by means of ring-shaped waveguide with subsequent radiotherapy and results of its theoretical and ex- perimental studies. Experimental studies were performed in vivo on white rats with inoculated sarcoma M-1 tumours. Treatment was performed using ultrasound with frequency 22-23 kHz and intensity about 2 W/cm2. Ultrasonic treatment was proved to be an efficient modifier of radiotherapy. It describes results of experimental and theoretical studies of behav- iour of granular media (powder materials) in airborne ultrasonic field created by flexurally-vibrating ring-shaped waveguide with resonant frequency in the range 20-40 kHz. Experimental observations are compared with results of model- ling of acoustic radiation force field inside the ring by means of COMSOL Multiphysics and MathCad software. There are shows the results of temperature measuring of tissue phantom and radiation pressure on ring axis. It proves the possibility of contactless therapy of skin tumours.