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https://elib.bsu.by/handle/123456789/49642| Title: | Физико-химическая регуляция митохондриального транспорта электронов в опухолевых клетках с участием редокс-активных молекул |
| Authors: | Голубева, Е. Н. Мартинович, Г. Г. |
| Keywords: | ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Химия |
| Issue Date: | 2012 |
| Citation: | Сборник научных работ студентов Республики Беларусь "НИРС 2011". - Минск, 2012. - С. 43-44 |
| Abstract: | In our investigations the production of reactive oxygen species (ROS) in human larynx carcinoma cells HEp-2 was observed. Mitochondria were established to be the main source of ROS in HEp-2 cells. ROS formation was caused by the forward electron transport in complex I. Supplement of physiological concentrations of ascorbic acid (AA) changed the direction of electron transfer in complex I of the mitochondrial respiratory chain. In presence of AA at physiological concentrations a decrease in ascorbate- and antimycin-induced ROS generation was also observed |
| URI: | http://elib.bsu.by/handle/123456789/49642 |
| Appears in Collections: | Сборник научных работ студентов Республики Беларусь "НИРС 2011" |
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