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https://elib.bsu.by/handle/123456789/240037
Полная запись метаданных
Поле DC | Значение | Язык |
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dc.contributor.author | Istomin, Y. P. | - |
dc.contributor.author | Alexandrova, E. N. | - |
dc.contributor.author | Zhavrid, E. A. | - |
dc.contributor.author | Voropay, E. S. | - |
dc.contributor.author | Samtsov, M. P. | - |
dc.contributor.author | Kaplevsky, K. N. | - |
dc.contributor.author | Lugovsky, A. P. | - |
dc.contributor.author | Lugovsky, A. A. | - |
dc.date.accessioned | 2020-02-13T09:33:26Z | - |
dc.date.available | 2020-02-13T09:33:26Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Experimental Oncology 28, 80–82, 2006 (March) | ru |
dc.identifier.uri | http://elib.bsu.by/handle/123456789/240037 | - |
dc.description.abstract | Aim: To evaluate the effect of cell oxygenation onphotocytotoxicity of a novel tricarbocyanine indolenine dye covalently bound to glucose(TICS). Methods: HeLa cells were incubated with 5 μM TICS, 2 h later irradiated by laser at 740 nm with a light dose of 10 J/cm2, delivered at a power density of 10, 20, 25 or 30 mW/cm2, in air or in argon atmosphere, and then scored for viability. Results: The photocytotoxicity of TICS increased dramatically as the power density was reduced. Under hypoxia TICS-photosen-sitized cell death was determined but its value was lowered, compared to photoirradiation in the air. Conclusion: Photosensitizing effect of TICS is only partially dependent on the oxygenation of tumor cells.Key Words:photosensitizers, cyanine dyes, HeLa cells, photodynamic therapy, hypoxia. | ru |
dc.language.iso | en | ru |
dc.publisher | Украина: Киев | ru |
dc.subject | ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Физика | ru |
dc.subject | ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Биология | ru |
dc.title | Еhe effect of hypoxia on photocytotoxicity of tics tricarbocyanine dye in vitro | ru |
dc.type | article | ru |
dc.rights.license | CC BY 4.0 | ru |
Располагается в коллекциях: | Кафедра лазерной физики и спектроскопии (статьи) |
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Файл | Описание | Размер | Формат | |
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17-Istomin.pdf | 163,56 kB | Adobe PDF | Открыть |
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