Studying of genome–specificity of triplet periodicity

Abstract

Triplet periodicity (TP) is distinguishing property of protein coding sequences of both prokaryote and eukaryote genomes which studied for decades. In the work we explored distributions of triplet periodicity difference inside and between bacterial genomes. We constructed two hypothesis of TP distribution on set of coding sequences and simulated corresponding artificial datasets. We found that triplet periodicity is more similar inside genome than between genomes and that TP distribution inside genome corresponds to hypothesis which imply common TP pattern for majority of sequences.