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Please use this identifier to cite or link to this item: https://elib.bsu.by/handle/123456789/94560
Title: Structurally resolved stochastic simulation model of actin polymerization
Authors: Chukhutsina, V. V.
Halavatyi, A. A.
Yatskou, M. M.
Friederich, E.
Apanasovich, V. V.
Keywords: ЭБ БГУ::ОБЩЕСТВЕННЫЕ НАУКИ::Информатика
Issue Date: 2010
Publisher: Minsk: BSU
Abstract: Actin polymerization in cell is a basic biological process relevant to health and disease. We have developed the e±cient stochastic simulation algorithm for modelling actin dynamics regulated by actin-associated proteins. As opposed to other existing actin-cytoskeleton mathematical models, our approach is based on the advanced Monte Carlo simulation schemes and associates the main biochem- ical actin-related reactions, including multistep spontaneous actin nucleation, random and stress-induced Їlament fragmentation, with structural properties of protein Їlaments. Created algorithms were integrated into a freely available software package with user-friendly interface.
URI: http://elib.bsu.by/handle/123456789/94560
Appears in Collections:Section 5. COMPUTER SIMULATION OF STOCHASTIC SYSTEMS

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