Effects of biphenol and quinone derivatives on the radiation-initiated dephosphorylation of 1-glycerophosphate

Abstract

The effects of biphenol and quinone derivatives on the radiation-initiated dephosphorylation of 1-glycerophosphate under various conditions were studied. It was found that in deaerated media, para- and ortho-quinone derivatives inhibited the formation of the phosphate ion by a factor of 1.8-1.9, and hydroquinone and pyrocatechol derivatives inhibited this reaction by a factor of 1.3-1.4, whereas 5-methylresorcinol and 2-methoxyphenol had no effect on the elimination of inorganic phosphate. It was demonstrated that a decrease in the radiation-chemical yields of the phosphate anion was due to the oxidation of 1-glycerophosphate radicals, which were formed under γ-radiolysis in aqueous solutions, by quinones.