Об участии мочевины крови и L-аргинин-NO-системы печени в регуляции температуры тела при эндотоксиновой лихорадке

Abstract

Сomprehensive study of the role of urea and L-arginine-NO-pathway in the liver in the pathogenesis of endotoxin fever and antipyretic mechanisms gave the basis to conclude that the level of urea in the blood can determine L-arginine-NO-pathway activity in the liver during bacterial endotoxemia and, thus, makes the important contribution to the pathogenesis of fever