Восстановление лигандсвязывающего потенциала вне- и внутриклеточных транспортных систем при внепеченочном холестазе c помощью экстрактов из семян расторопши, лофанта, горца и душицы

Abstract

Possibility of reduction of ligand binding potential of albumin and glutathione S-transferases under extrahepatic cholestasis using extracts from seeds of Silybum marianum, Aconogonon Weyrichii, Lophanthus virescens, Origanum vulgare was studied. Analysis of acquired results testifies to the fact, that the greatest positive effect concerning extra- and intrahepatic transport systems was observed under treatment with extract from the seeds of Silybum marianum, that is traditionally used for cure of liver deseases. Influence of extract from Lophanthus virescens was not less effective by a number of activities. Extracts from the Aconogonon Weyrichii and Origanum vulgare have had less positive effect. Phenomenon of reduction of Iigand binding potential of intrahepatic as well as extrahepatic transport systems under influence of investigated extracts allows to predict their high effectiveness under cholestasis and liver chirrosis.