Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на этот документ:
https://elib.bsu.by/handle/123456789/289093
Заглавие документа: | Bacterial cellulose-based nanocomposites containing ceria and their use in the process of stem cell proliferation |
Авторы: | Gofman, Iosif V. Nikolaeva, Alexandra L. Khripunov, Albert K. Ivankova, Elena M. Shabunin, Anton S. Yakimansky, Alexander V. Romanov, Dmitriy P. Popov, Anton L. Ermakov, Artem M. Solomevich, Sergey O. Bychkovsky, Pavel M. Baranchikov, Alexander E. Ivanov, Vladimir K. |
Тема: | ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Физика ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Химия |
Дата публикации: | 2021 |
Издатель: | MDPI AG |
Библиографическое описание источника: | Polym 2021;13(12). |
Аннотация: | A technique for the fabrication of bacterial cellulose-based films with CeO2 nanofiller has been developed. The structural and morphological characteristics of the materials have been studied, their thermal and mechanical properties in dry and swollen states having been determined. The preparation methodology makes it possible to obtain composites with a uniform distribution of nanoparticles. The catalytic effect of ceria, regarding the thermal oxidative destruction of cellulose, has been confirmed by TGA and DTA methods. An increase in CeO2 content led to an increase in the elastic modulus (a 1.27-fold increase caused by the introduction of 5 wt.% of the nanofiller into the polymer) and strength of the films. This effect is explained by the formation of additional links between polymer macro-chains via the nanoparticles’ surface. The materials fabricated were characterized by a limited ability to swell in water. Swelling caused a 20-to30-fold reduction in the stiffness of the material, the mechanical properties of the films in a swollen state remaining germane to their practical use. The application of the composite films in cell engineering as substrates for the stem cells’ proliferation has been studied. The increase in CeO2 content in the films enhanced the proliferative activity of embryonic mouse stem cells. The cells cultured on the scaffold containing 5 wt.% of ceria demonstrated increased cell survival and migration activity. An analysis of gene expression confirmed improved cultivation conditions on CeO2-containing scaffolds. |
URI документа: | https://elib.bsu.by/handle/123456789/289093 |
DOI документа: | 10.3390/polym13121999 |
Scopus идентификатор документа: | 85108707845 |
Финансовая поддержка: | Russian Foundation for Basic Research (20-33-70236); Ministry of Education and Science of the Russian Federation |
Лицензия: | info:eu-repo/semantics/openAccess |
Располагается в коллекциях: | Статьи сотрудников НИИ ФХП |
Полный текст документа:
Файл | Описание | Размер | Формат | |
---|---|---|---|---|
polymers-13-01999.pdf | 5,38 MB | Adobe PDF | Открыть |
Все документы в Электронной библиотеке защищены авторским правом, все права сохранены.